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Health and medicine

Scientists and policymakers use scenarios called Shared Socioeconomic Pathways to project how today’s choices affect tomorrow’s world. But for complex subjects like public health, these intentionally simple scenarios don’t capture every complexity.

Explore recent research from the Ä¢¹½ÊÓÆµ: ancient capybara and palm fossils found in the desert, a window into the bottom of the food web, waves that go a different way, environmental advocacy in Colombia, the mechanics of blood clotting and a superconducting surprise.

American public health agencies don’t routinely test wastewater for sexually transmitted infections, but new research led by the Ä¢¹½ÊÓÆµ and the Washington State Department of Health found that such methods could be used to effectively identify Chlamydia trachomatis, the bacteria that causes chlamydia.

Researchers at the Ä¢¹½ÊÓÆµ are investigating how genetic changes impact the severity of schizophrenia symptoms. A new study supports the idea that deletions in genes that regulate early brain and neuron development are associated with more severe features of schizophrenia spectrum disorders, particularly lower cognitive abilities.

Housed in the Ä¢¹½ÊÓÆµ School of Pharmacy, the Institute for Innovations in Drug Delivery and Disposition (I2D3) brings together experts in artificial intelligence, drug discovery, pharmacology, data science and biotechnology to ease the bottleneck between promising molecules and successful drugs. 

To rebalance the oral microbiome and cure chronic halitosis, researchers at the Ä¢¹½ÊÓÆµ are embarking on a first-of-its-kind experiment. These clinical trials transplant bacteria and other minuscule critters from healthy donors into patients with halitosis. If successful, the healthy microbiota will crowd out the bad and patients’ bad breath will improve.

In mid-pregnancy, exposure to any smoke was associated with an elevated risk of preterm birth, with that risk peaking around the 21st week of gestation. In late pregnancy, elevated risk was most closely associated with exposure to high concentrations of wildfire PM2.5, above 10 micrograms per cubic meter.

Targeted drug delivery is a powerful and promising area of medicine. Therapies that pinpoint precise areas of the body can reduce the medicine dosage and avoid potentially harmful “off targetâ€� effects. Researchers at the Ä¢¹½ÊÓÆµ took a significant step toward that goal by designing proteins with autonomous decision-making capabilities. By adding smart tail structures to therapeutic proteins, the team demonstrated that the proteins could be “programmedâ€� to act based on the presence of specific environmental cues.

Two Ä¢¹½ÊÓÆµ researchers are developing treatments that aim to simultaneously treat cancer and improve patients’ quality of life. For World Cancer Day, Ä¢¹½ÊÓÆµ News asked them to discuss their novel materials and how these materials can treat both the cancer and the patient.

Workers from small, rural communities often move into the outer edges of cities, which offer greater economic opportunities but often have low-quality housing that is likely to suffer greater damage during an earthquake. The risk grows even more when migrants come from low-income or tribal villages.

In just eight years, the Ä¢¹½ÊÓÆµ Population Health Initiative has funded 227 innovative, interdisciplinary projects. With the Initiative now a third of the way into its 25-year vision, Ä¢¹½ÊÓÆµ News checked in with three projects that recently received funding to scale their efforts. 

Young adults with psychosis tend to use cannabis at extremely high rates, and their symptoms can be exacerbated by long-term marijuana use. A team of Ä¢¹½ÊÓÆµ researchers is focused on this particular group. 

Fifteen faculty members at the Ä¢¹½ÊÓÆµ have been elected to the Washington State Academy of Sciences for 2024. They are among 36 scientists and educators from across the state announced Aug. 1 as new members. Selection recognizes the new members’ “outstanding record of scientific and technical achievement, and their willingness to work on behalf of the academy to bring the best available science to bear on issues within the state of Washington.â€�

As often as four days a week, Boeing EA-18G Growler electronic attack aircraft based at Naval Air Station Whidbey Island fly loops overhead as pilots practice touch-and-go landings. The noise is immense. New research from the Ä¢¹½ÊÓÆµ shows that the noise isn’t just disruptive — it presents a substantial risk to public health.

Working with teens, Ä¢¹½ÊÓÆµ researchers have designed RESeT: a snowy virtual world with six activities intended to improve mood. In a 3-week study of 44 Seattle-area teens, researchers found that most used the technology about twice a week without being prompted and reported lower stress levels after using the environment.

Starting in the earliest days of the 2020 outbreak, a team of researchers at the Ä¢¹½ÊÓÆµ conducted real-time surveys of King County residents, asking what measures people had taken to protect themselves, how their daily lives had been affected and what worried them most.  

A new Ä¢¹½ÊÓÆµ study places the prevalence of immunosuppression at around 6.6% of American adults — more than twice as high as previously understood. That rise could have broad implications for how we navigate the late stages of COVID-19 and prepare for future pandemics.  

With several university athletic programs around the country — including the Ä¢¹½ÊÓÆµ — announcing moves to new conferences that will likely increase travel for student-athletes, a group of sleep and circadian scientists and physicians have published a white paper describing the significance of repeated, chronic jet lag on student-athlete health and performance — both in academics and in sports, and suggesting strategies to reduce the consequences of travel across time zones.

Currently, more than half of all cervical cancers diagnosed in the United States are in people who are overdue for screening or have never been screened. In a new study, researchers report that mailing HPV test kits significantly increased cervical cancer screening rates.

Two years ago, as life regained its rhythm and public transit once again filled with people, train and bus operators spotted a troubling trend. Some operators reported instances of people smoking drugs on their vehicles, and worried that the haze it created could linger, potentially affecting workers’ physical and mental health.  Spurred by operators’ concerns, five transit agencies in Washington and Oregon approached researchers at the Ä¢¹½ÊÓÆµ with a yes-or-no question: Were transit operators being exposed to drug…

The case studies in Medicine for a Changing Planet, collated from clinical encounters around the world, support health professionals in recognizing and treating a variety of health-related conditions that can be traced to environmental stressors.

On July 13, the Food and Drug Administration approved for the first time an over-the-counter birth control pill, expected to hit shelves in early 2024. The approval of the oral contraceptive Opill could drastically expand access to birth control, which for decades has been available only through a prescription. It’s a rare victory for reproductive rights — and the culmination of a 25-year effort to land birth control on drugstore shelves.   A central player in that push was Donald Downing,…